Behavior of fibrinogen in diabetic patients in comparison with objective vascular measurements in the ocular fundus
Syrbe, G.; Oswald, B.; Jorke, D.; Jütte, A.
Folia Haematologica 112(6): 853-858
1985
ISSN/ISBN: 0323-4347 PMID: 2419213 Document Number: 248344
Objective measurements of vessels were performed in vivo in 10 patients affected with diabetes mellitus, the fibrinogen concentrations in the venous blood being determined simultaneously. Whereas the ensured correlations with fibrinogen concentration could be recognized from the diameter of arteries and veins and from the flow velocity, a linear correlation could be found to exist between the fibrinogen level and the volume flowing through a retinal artery. These findings prove that the very existence of a hyperfibrinogen anemia does not justify the assumption of the blood volume flow being decreased. In patients with diabetes mellitus the enhanced volume flowing through retinal arteries is rather connected with an increased fibrinogen level.