Incidence of spina bifida occulta in relatives of children with myelodysplasia. Indications for high-risk screening

Jährig, K.; Wüchner, U.

Zentralblatt für Gynakologie 107(13): 821-826

1985


ISSN/ISBN: 0044-4197
PMID: 3898657
Document Number: 248165
Consanguineous relatives (parents, siblings) of patients with myelodysplasia show an increased incidence of spina bifida occulta compared to a normal population. According to this and considering the obvious familiarity of neural tube defects, in all cases of a spina bifida occulta known in relatives a high-risk-screening (AFP, B-scan ultrasound) should be performed during early pregnancy. Patients with a spina bifida occulta should be informed about their anomaly and in case of pregnancy instruct the obstetrician to provide a careful screening examination.

Document emailed within 1 workday
Secure & encrypted payments