The biology of papillomaviruses and their role in oncogenesis
Smith, K.T.; Campo, M.S.
Anticancer Research 5(1): 31-47
1985
ISSN/ISBN: 0250-7005 PMID: 2986520 Document Number: 247591
A large number of different papillomavirus types have been identified. Several viruses often infect the same species and each virus is associated with a defined tissue. Recent evidence has shown that certain benign lesions can undergo malignant transformation in both animals and humans in response to genetic or environmental factors. Fine mapping of the structure and function of the viral genome may enhance our understanding of the interaction between the virus and the cofactors involved in malignant transformation.