Circulating immune complexes (CIC) as tumor marker in the follow-up of breast cancer
Neri, B.; Comparini, T.; Ciatto, S.; Cataliotti, L.; Distante, V.; Bartalucci, S.
Cancer Detection and Prevention 8(1-2): 53-56
1985
ISSN/ISBN: 0361-090X PMID: 4064052 Document Number: 243393
We report on the possible diagnostic and prognostic role of circulating immune complexes (CIC) determination in breast cancer. A sensitivity of 87% and a specificity of 90% were observed in a case-control study of 15 cancers and 25 noncancer healthy controls. A direct correlation of CIC level to the presence and probably to the entity of the tumor mass was assessed by comparing preoperative to postoperative CIC determinations in cancer cases: CIC levels were significantly lower after tumor removal. These preliminary results suggest further studies on the use of CIC determination in the follow-up of breast cancer for the early diagnosis of recurrent disease.