Characteristics of the functional activity of leukocytes in diabetes mellitus
Galenok, V.A.; Bondar', I.A.
Terapevticheskii Arkhiv 57(12): 16-19
1985
ISSN/ISBN: 0040-3660 PMID: 4089762 Document Number: 242723
A study was made of the mechanisms of leucocyte phagocytic and bactericidal activity with relation to Staph, aureus and the NBT-test in simple and simulated variants in 71 patients with diabetes mellitus. A compensatory elevation of the phagocytic index and the phagocytic number was found in all the patients with a decrease in phagocytosis completion which testified to the internal defects of bactericidal activity which, according to the NBT-test results, consisted in insufficient activity of oxidation enzymes. The stimulated NBT-test showed a decrease in phagocytic potentialities in patients with diabetes mellitus. Phagocytosis defects in type I and type II diabetes mellitus were more noticeable in a severe and labile course of the disease.