Immunologic studies of progeny of atopic dogs
Schwartzman, R.M.
American Journal of Veterinary Research 45(2): 375-378
1984
ISSN/ISBN: 0002-9645 PMID: 6711964 Document Number: 241448
Atopic dogs were bred to establish a colony of progeny predisposed to develop type I hypersensitivity. In a 2-year period, 72 pups were born and were monitored for clinical evidence and immunological "markers" of atopic disease. Thirteen dogs in the colony, belonging to the oldest age group, manifested clinical signs compatible with atopic disease. Immunological variables relative to serum IgE levels, parasitic infection, and duration of severity of clinical signs of disease were studied in this group. Analysis of these data did not identify indicators which could be used to predict the development of the atopic state in dogs.