Electron microscopic and radioautographic study of nucleic acid synthesis in normal fatty tissue and lipomas
Sarkisov, D.S.; Pal'tsyn, A.A.; Adamian, A.A.; Kolokol'chikova, E.G.
Biulleten' Eksperimental'noi Biologii i Meditsiny 97(5): 618-621
1984
ISSN/ISBN: 0365-9615 PMID: 6202340 Document Number: 239229
Electron microscopic radioautography was used to study nucleic acid synthesis in the normal fatty tissue and lipomas of different degree of maturity. Destroyed adipocytes were found in the investigated varieties of the fatty tissue. In a slow-growing Madelung's lipoma such adipocytes occurred in a greater amount than in the normal fatty tissue and nongrowing lipomas. 3H-Thymidine was mainly incorporated by endotheliocytes and pericytes, whereas Madelung's lipoma contained a greater number of labeled cells. Based on the data obtained it is suggested that the replenishment of adipocytes occurs at the expense of the proliferation of vascular wall cells.