Screening for endometrial carcinoma in a group at risk
Morack, G.; Ebeling, K.; Flach, W.; Peschel, H.G.; Pockrandt, H.
Archiv für Geschwulstforschung 54(5): 415-422
1984
ISSN/ISBN: 0003-911X PMID: 6497587 Document Number: 239108
In a population-based study 923 asymptomatic women with diabetes aged 40 to 70 years were investigated by aspiration curettage. The samples were evaluated histologically. During the initial screening 4 histologically proved endometrial cancers were diagnosed. All cancer patients were additionally obese and had hypertension, with one exception they were also nulliparous. During the same period the expected number of cases for all investigated women was estimated to 0,74. The expected number of cases limited to those with diabetes, obesity and hypertension was 0,31; and limited to those with diabetes, obesity, hypertension and nulliparity was 0,1, respectively. Additionally 4 cases of adenomatous hyperplasia of the endometrium were identified. The long-term impact on morbidity and mortality of endometrial cancer within the investigated population at risk cannot be assessed as yet.