Biochemical monitoring of the insufficient systemic perfusion in bronchiolitis
Picciocchi, R.; Vetrano, A.; Maddalena, M.; Martinelli, R.; Mabilia, R.; Trischitta, V.; Spadaro, G.
La Pediatria Medica e Chirurgica Medical and Surgical Pediatrics 6(6): 777-779
1984
ISSN/ISBN: 0391-5387 PMID: 6545589 Document Number: 238400
Biochemical monitoring was performed on 113 sucklings affected with bronchiolitis in order to evaluate early onset of insufficient systemic perfusion. Values of haematic lactate, GPT and CPK levels in the serum, partial tension of haematic gases were evaluated on first day of hospitalization. Haemogasanalytic monitoring made it possible to differentiate two groups of infants: 21 patients with hypoxemia and 92 patients with normoxemia. Monitoring of lactatemia, CPK and GPT activity evidenced following values: hyperlactemia (66.6%), increased CPK levels (47.6%), increased GPT levels (14.2%) in the group of infants with hypoxemia. Hyperlactemia (55.4%), increased CPK levels (62%), increased GPT levels (19.5%) in the group of patients with normoxemia. These findings show no significant difference between the two groups and frequent occurrence of tissular hypoxia attributable to insufficient systemic perfusion. Moreover the results of such biochemical monitoring permit precise indication about appropriate treatment.