Mucosal leishmaniasis in an Indian AIDS patient
Singh, S.
Lancet. Infectious Diseases 4(11): 660-661
2004
ISSN/ISBN: 1473-3099 PMID: 15522675 DOI: 10.1016/s1473-3099(04)01179-xDocument Number: 237351
A case of mucosal leishmaniasis is reported in a 38-year-old man from the kala-azar-endemic state of Bihar who presented in June 2003 to the All India Institute of Medical Sciences, New Delhi, India for nodular lesions on his chin, oral mucocutaneous junctions, tongue, soft and hard palate, nasal mucosa, and conjunctiva since February 2003. These nodules had not responded to antibiotics and topical steroid treatment given by local physicians. Biopsy samples taken from the palatal nodule revealed dense cellular infiltrates with histiocytes, lymphocytes and plasma cells. Past history revealed that in March 2003, he had gluteal herpes zoster and hepatomegaly on ultrasonography with consistent leukopenia. In September 2002, he had parasitologically proven kala-azar and received 35 injections of sodium antimony gluconate locally. The patient was tested positive for HIV-1 and anti-rK-39 antibodies for leishmaniasis. The patient was treated successfully with intravenous sodium antimony gluconate and rifampicin for 20 days, and he was put on highly active antiretroviral therapy for HIV co-infection. Lesions disappeared completely within one month. The patient was symptom-free during follow-up in June 2004.
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