In vivo injection of dipyridamole stimulates the synthesis of prostacyclin-like substances in human varicose veins
Fahr, A.; Langer, R.; Sziegoleit, W.; Beitz, J.; Krause, P.; Förster, W.
Biomedica Biochimica Acta 43(3): K6-K8
1984
ISSN/ISBN: 0232-766X PMID: 6378192 Document Number: 237350
The influence of dipyridamole, given by a bolus injection (30 mg i. v.) on the synthesis of prostacyclin-like substances (PGI2-LS) in human shank varicose veins was investigated. The pretreatment with dipyridamole enhances the second step in PGI2 biosynthesis (transformation of endoperoxide to PGI2) in these preparations.
Document emailed within 1 workday
Related Documents
Costantini, V.; Talpacci, A.; Bastiano, M.L.; Boschetti, E.; Cipolloni, S.; Bisacci, R.; Nenci, G.G. 1990: Increased prostacyclin production from human veins by dipyridamole: an in vitro and ex vivo study Biomedica Biochimica Acta 49(4): 263-271Carter, A.J.; Eisert, W.G.; Müller, T.H. 1989: Thrombin stimulates inositol phosphate accumulation and prostacyclin synthesis in human endothelial cells from umbilical vein but not from omentum Thrombosis and Haemostasis 61(1): 122-126
Schmidt, C.; Baumeister, B.; Kipnowski, J.; Miederer, S.E.; Vetter, H. 1998: Magaldrate stimulates endogenous prostaglandin E2 synthesis in human gastric mucosa in vitro and in vivo Hepato-Gastroenterology 45(24): 2443-2446
Groves, H.M.; Kinlough-Rathbone, R.L.; Cazenave, J.P.; Dejana, E.; Richardson, M.; Mustard, J.F. 1982: Effect of dipyridamole and prostacyclin on rabbit platelet adherence in vitro and in vivo Journal of Laboratory and Clinical Medicine 99(4): 548-558
Dee, R. 1999: A logical approach to the injection treatment of varicose and "spider" veins Connecticut Medicine 63(7): 391-398
Christensen, T.E.; Schnohr, E. 1975: Treatment of varicose veins by injection of hydroxypolyethoxy-dodecane (Aethoxysclerol) Ugeskrift for Laeger 137(15): 836-837
Herrmann, M. 1992: Surgery of varicose veins and varicose complications in a tropical country. a personal experience Helvetica Chirurgica Acta 58(6): 795-799
Miller, V.M.; Rud, K.S.; Gloviczki, P. 2000: Pharmacological assessment of adrenergic receptors in human varicose veins International Angiology: a Journal of the International Union of Angiology 19(2): 176-183
Diehm, C.; Diehm, N. 2002: Kneipp hydrotherapy, sclerotherapy, crossectomy. what really helps in varicose veins and spider veins? MMW Fortschritte der Medizin 144(35-36): 22-27
Sukovatykh, B.S.; Nazarenko, P.M.; Belikov, L.N. 1992: The mechanisms of the development of vertical blood reflux through the deep veins in varicose veins Vestnik Khirurgii Imeni I. I. Grekova 149(11-12): 330-335
Urigo, F.; Pischedda, A.; Mocci, M.; Carpanese, L.; Canalis, G.C. 1992: Incompetence of the m. gemellus veins in varicose veins: its incidence and phlebographic study La Radiologia Medica 84(1-2): 48-53
Burnand, K.G.; O'Donnell, T.F.; Thomas, M.L.; Browse, N.L. 1977: The relative importance of incompetent communicating veins in the production of varicose veins and venous ulcers Surgery 82(1): 9-14
Fuchs, U.; Petter, O. 1990: Morphologic studies of the conductive veins of the leg in superficial varicose veins Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 45(4): 121-123
Leseche, G.; Bikfalvi, A.; Dupuy, E.; Tobelem, G.; Andreassian, B.; Caen, J. 1989: Prelining of polytetrafluoroethylene grafts with cultured human endothelial cells isolated from varicose veins Surgery 105(1): 36-45
Geier, B.; Barbera, L.; Mumme, A.; Köster, O.; Marpea, B.; Kaminsky, C.; Asciutto, G. 2007: Reflux patterns in the ovarian and hypogastric veins in patients with varicose veins and signs of pelvic venous incompetence Chirurgia Italiana 59(4): 481-488
Recek, C.; Koudelka, V. 1973: Perforating veins of the leg and their role in the pathogenesis of varicose veins Rozhledy V Chirurgii: Mesicnik Ceskoslovenske Chirurgicke Spolecnosti 52(1): 14-20
Koroloev, B.A.; Makarov, N.A.; Zharikov, V.I.; Kulikov, N.V. 1979: Subfascial ligation of the communicating crural veins in the comprehensive surgical treatment of varicose veins of the lower extremities in light of the late results Vestnik Khirurgii Imeni I. I. Grekova 123(10): 84-88
Jeremy, J.Y.; Gill, J.; DuBourg, A.; Pelat, P.; Mikhailidis, D.P. 1993: Effect of buflomedil on in vitro prostacyclin and endothelin synthesis by vascular (rat and human) and penile (rat) tissue and calcium uptake by isolated human platelets International Journal of Impotence Research 5(3): 139-147
Ristimäki, A. 1989: Transforming growth factor alpha stimulates prostacyclin production by cultured human vascular endothelial cells more potently than epidermal growth factor Biochemical and Biophysical Research Communications 160(3): 1100-1105
Mentz, P.; Pönicke, K.; Block, H.U.; Giessler, C.; Blass, K.E.; Bayer, B.L.; Förster, W. 1981: Stimulation of prostacyclin biosynthesis as a possible mechanism of action of dipyridamole Arzneimittel-Forschung 31(12): 2075-2082