Analytical methods for quantitation of methylxanthines
Hurst, W.J.; Martin, R.A.; Tarka, S.M.
Progress in Clinical and Biological Research 158: 17-28
1984
ISSN/ISBN: 0361-7742 PMID: 6396643 Document Number: 237026
The methylxanthines can be determined in foods and biological systems by the chromatographic methods of TLC, GC, and HPLC. Ultraviolet spectroscopy following a separation procedure is also still used. More recently immunoassay methods have been developed. There is no single best method; the analyst must balance the features of each assay with the final requirements for data precision and reproducibility.