Intrauterine infection after delivery: a marker of HIV-1 seropositivity among puerperal women in Uganda?
Okong, P.; Biryahwaho, B.; Bergstrom, S.
International Journal of Std and Aids 15(10): 669-672
2004
ISSN/ISBN: 0956-4624 PMID: 15479503 DOI: 10.1177/095646240401501007Document Number: 236264
A case controlled study about HIV seroprevalence among women with postpartum endometritis-myometritis (PPEM) matched with two controls. Each was performed in a non-governmental organization hospital in Kampala, Uganda. All participants were offered HIV pre- and post-test counselling. Personal and clinical information was obtained and HIV-1 ELISA tests performed on blood samples and discordant results resolved by Western blot test. HIV-1 seroprevalence was significantly higher among women with PPEM than controls, 26 (42.3%) and 26 (21.3%) respectively (P = 0.002). Women with PPEM were two-and-a-half times more likely to be HIV-positive than controls, odds ratio 2.74 (95% Cl 1.34-5.65). Single or cohabiting women and low salaried women were also significantly more among PPEM cases than controls. In conclusion, PPEM cases had significantly higher seroprevalence of HIV-1 infection than controls and this needs further elucidation for purposes of management strategies.