Clinical pharmacokinetics of mebikar
Serov, N.V.; Treskov, V.G.; Berliand, A.S.; Knizhnik, A.Z.; Lapin, K.V.
Farmakologiia i Toksikologiia 47(3): 94-97
1984
ISSN/ISBN: 0014-8318 PMID: 6734814 Document Number: 236046
Twenty-two patients admitted to the narcological clinic of an industrial enterprise were examined for the clinical effect and pharmacokinetic parameters after intake of a single dose of a Soviet psychotropic drug mebicar. The clinical status was assessed by means of psychometric mapping and concurrent recording of the EEG. The correlation of the pharmacodynamic and pharmacokinetic data can be used for the choice of minimal effective concentrations applied in further calculations of individual dosage regimens.