Tyramine is a major mutagen precursor in soy sauce, being convertible to a mutagen by nitrite
Ochiai, M.; Wakabayashi, K.; Nagao, M.; Sugimura, T.
Gan 75(1): 1-3
1984
ISSN/ISBN: 0016-450X PMID: 6373470 Document Number: 235192
Tyramine was identified as a new mutagen precursor in Japanese soy sauce, becoming mutagenic after treatment with nitrite under acidic conditions. The mutagenic compound was identified as 4-(2-aminoethyl)-6-diazo-2,4- cyclohexadienone , and its specific mutagenic activity was 112 revertants/micrograms towards Salmonella typhimurium TA100 without S9 mix.