Double balanced de novo translocations involving chromosomes 4/15 and 5/12 in a mentally retarded boy
Li, S.Y.; Jong, R.H.; Chow, M.C.; Jou, T.C.
Proceedings of the National Science Council Republic of China. Part B Life Sciences 8(1): 54-59
1984
ISSN/ISBN: 0255-6596 PMID: 6531417 Document Number: 235097
This report describes a compound structural rearrangement containing two apparently unrelated reciprocal translocations, one between chromosomes 4 and 15, the other between 5 and 12. It is suggested that the patient's mental retardation and osteosclerosis may be the result of the loss of a small amount of chromosomal material and/or position effect accompanying these translocations.