Metabolic transformation affected by specific Salmonella O antigen in the lymphocytes of salmonellosis patients
Bunin, K.V.; Kosiakova, N.I.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 5: 77-79
1984
ISSN/ISBN: 0372-9311 PMID: 6204475 Document Number: 235042
Metabolic transformation in the lymphocytes of salmonellosis patients, manifested by changes in the proportion of nucleic acids due to the stimulating action of Salmonella specific O antigen, was studied by the method of microspectral luminescent analysis. The level of single-helix nucleic acids in lymphocytes was shown to increase 6-8 hours after the stimulating action of specific O antigen, which was manifested by the increase of the alpha parameter from 0.21 to 0.68 in salmonellosis patients. This made it possible to confirm the diagnosis of salmonellosis in 92-95% of cases even at the early period of the disease when serodiagnosis could not yet be made.