Components of selection in X chromosome lines of Drosophila melanogaster: sex ratio modification by meiotic drive and viability selection
Curtsinger, J.W.
Genetics 108(4): 941-952
1984
ISSN/ISBN: 0016-6731 PMID: 6439600 Document Number: 233063
Selection coefficients and segregation parameters have been estimated in 18 randomly chosen lines carrying wild X chromosomes on the cn bw genetic background. Each line was studied in replicated crosses of four types, with approximately 100 replications per line per cross. Crosses in which male X chromosomes differed exhibited significant sex ratio heterogeneity. Maximum likelihood estimation of segregation parameters revealed two lines in which the proportion of X-bearing gametes produced by males was significantly different from Mendelian expectations. These observations suggest that segregation distortion is a common feature of naturally occurring genetic variation. Non-Mendelian segregation has important evolutionary implications.