Incidence of neonatal infection in newborn infants with a maternal history of premature rupture of membranes (PROM) for 18 hours or longer by using Phramongkutklao Hospital Clinical Practice Guideline (CPG)
Ratanakorn, W.; Srijariya, W.; Chamnanvanakij, S.; Saengaroon, P.
Journal of the Medical Association of Thailand 88(7): 973-978
2005
ISSN/ISBN: 0125-2208 PMID: 16241028 Document Number: 2320
Background. Phramongkutklao CPG was developed for detecting infants with maternal PROM >= 18 hours who had a high risk of infection.Objective: To determine efficacy of the CPG, and risk factors of infection.Study design: Prospective cohort study.Material and Method: Eligible infants were categorized into group I (symptomatic), group II (chorioamnionitis) or group III (asymptomatic). Infants in group I, II and those in group III who had scores >= 3 were treated with antibiotics. Infants were followed-up until 28 days of age.Results: 104 infants were recruited into the present study. 29 of 104 (27.88%) infants had infection. Risk factors were Apgar scores <= 5, PROM > 72 hours, gestational age < 34 weeks, and low birth weight. The success rate of using CPG was 98.08% and antibiotic use was reduced by 53.08%.Conclusion: Phramongkutklao CPG on PROM is safe and cost saving. All risk factors should be included in the guideline.
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