The mouse footpad test--sensitive to small proportions of drug-resistant bacilli in a sample of M. leprae
Almeida, J.G.; Joseph, P.S.; Sarangapani, G.; Chacko, C.J.
Indian Journal of Leprosy 56(1): 10-14
1984
ISSN/ISBN: 0254-9395 PMID: 6384379 Document Number: 230841
In experiments at the Radda Barnen Research Laboratories of the SLR & TC Karigiri, the mouse footpad test was demonstrated to detect DDS-resistant M.leprae even if as few as 0.1% (1 in 1000) of the M. leprae tested were DDS-resistant. The mouse footpad test appears to be sensitive to minute proportions of drug-resistant bacilli in samples of M. leprae tested.
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