X-ray analysis of pepsin. VI. Atomic structure of the enzyme at 2-angstrom resolution
Andreeva, N.S.; Zhdanov, A.S.; Fedorov, A.A.; Gushchina, A.E.; Shutskever, N.E.
Molekuliarnaia Biologiia 18(2): 313-322
1984
ISSN/ISBN: 0026-8984 PMID: 6425642 Document Number: 230525
The crystallographic refinement of the pepsin structure at 2 .ANG. resolution is described. Real space refinement and Jack and Levitt methods were used, resulting in the refined atomic coordinates of 2436 nonhydrogen atoms. Values of crystallographic R-factor and conformational energy are 29.2% and -1347 ccal/mol correspondingly. The most important and interesting features of pepsin structure are discussed.