Analysis of deuterated analogs of vitamin A by electron impact and chemical ionization modes in gas chromatography coupled to mass spectrometry

Cullum, M.E.; Olson, J.A.; Veysey, S.W.; Cullum, M.E; Olson, J.A; Veysey, S.W

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Analysis of deuterated analogs of vitamin A by electron impact and chemical ionization modes in gas chromatography coupled to mass spectrometry

Cullum, M.E.; Olson, J.A.; Veysey, S.W.

International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift für Vitamin- und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition 54(1): 3-10

1984

ISSN/ISBN: 0300-9831

PMID: 6735613

Document Number: 230308

To evaluate the total body reserves of vitamin A in humans, deuterated forms of vitamin A are potentially useful probes. Anhydroretinol was selected as a useful indicator of retinol isolated from plasma during GC/MS + molecular ion, analysis of anhydroretinol in the EI mode was a more appropriate and sensitive measure of retinol under these assay conditions.