Effect of venous stasis on vessel wall fibrinolysis
Stenberg, B.; Bylock, A.; Risberg, B.
Thrombosis and Haemostasis 51(2): 240-242
1984
ISSN/ISBN: 0340-6245 PMID: 6539959 Document Number: 230154
The effects of prolonged venous stasis on release of plasminogen activators (PA) from the caval vein of rats was studied. PA activity was continuously reduced in the intimal layer, and after 8 h of stasis, the reduction was statistically significant. After 2 and 3 days, no intimal PA activity was found. The PA activity in the adventitial vasa vasorum was unchanged during the experimental period.