Pharmacological characteristics of the acetylcholine and L-glutamate receptors of the subpharyngeal ganglion neuron in the mollusk Zachrysia guanensis
Martinez-Soler, R.; Mendez, R.; Gerateks, A.; Demushkin, V.P.; Pliashkevich, I.G.
Biulleten' Eksperimental'noi Biologii i Meditsiny 98(9): 312-315
1984
ISSN/ISBN: 0365-9615 PMID: 6091810 Document Number: 229598
The presence of acetylcholine and L-glutamate receptors sensitive to the cholinoreceptor-specific ligands cytizine and tubocurarine has been demonstrated by means of microapplication of acetylcholine and L-glutamate to the central parietal zone of the subpharyngeal ganglion of the mollusc Zachrysia guanensis. Azidocytizine inhibited the function of acetylcholine receptor but did not affect glutamate receptor. Based on the electrophysiological data and analysis of ligand conformations a model has been designed for a site where L-glutamine is recognized by glutamine receptor.