Allergic asthma from enzymes in drugs
Hartmann, A.L.; Wüthrich, B.; Baur, X.
Schweizerische Medizinische Wochenschrift 114(25): 916-917
1984
ISSN/ISBN: 0036-7672 PMID: 6205444 Document Number: 229332
Two patients, both non-atopic, developed asthma after exposure to drugs containing enzymes. RAST identified trypsin as the causative allergen in both cases, with, additionally, amylase and pepsin in the second patient. All enzymes so far recognized as respiratory allergens, and those widely used in drugs, are presented in tabular form.