Modification of selected leukocyte functions in albino rats caused by the transplantable Jensen sarcoma and by therapeutic trials of cyclophosphamide and vinblastine, Clostridium butyricum M55 and short-term hyperglycemia
Hambsch, K.; Henke, R.; Ludewig, R.
Archiv für Geschwulstforschung 54(5): 369-376
1984
ISSN/ISBN: 0003-911X PMID: 6497582 Document Number: 228433
A significant increase in leukocyte adhesion and agglomeration was observed in white rats with Jensen sarcoma. Glucose induced short-term hyperglycemia temporarily stimulated these leukocyte functions in healthy rats. This effect was not notably influenced by administration of tumorlyzing spores. In contrast administration of the cytostatic agents vinblastine and cyclophosphamide demonstrated dose-related inhibition of leukocyte agglomeration and adhesion.