Peptic lesions of the upper digestive tract and drugs. Prospective study
Gaillard, C.; Borel, G.A.; de Peyer, R.; Loizeau, E.
Schweizerische Medizinische Wochenschrift 114(2): 56-57
1984
ISSN/ISBN: 0036-7672 PMID: 6701485 Document Number: 227551
The association between drugs and diseases of the gastrointestinal tract is well known but has always been evaluated qualitatively and not quantitatively. To study the importance of this association, a prospective study was undertaken at the University of Geneva Hospital in 456 subjects. A statistically significant (p less than 0.05) correlation was found in the following associations: aspirin and multiple gastric ulcers, aspirin and severe erosive gastritis; non-steroidal antiinflammatory drugs and multiple duodenal ulcers, non-steroidal antiinflammatory drugs and mild erosive gastritis. On the other hand, no correlation was found between any of the observed gastrointestinal diseases and prednisone, alcohol or tobacco.