A new diterpene from Cupressus goveniana var. abramasiana: 5 beta-hydroxy-6-oxasugiol (cupresol)
Jolad, S.D.; Hoffmann, J.J.; Schram, K.H.; Cole, J.R.; Bates, R.B.; Tempesta, M.S.
Journal of Natural Products 47(6): 983-987
1984
ISSN/ISBN: 0163-3864 PMID: 6549469 Document Number: 227493
The petroleum ether-EtOH extract of C. goveniana var. abramasiana (Cupressaceae) yielded sugiol and the new diterpene, cupresol (5.beta.-hydroxy-6-oxasugiol), for which a structure was established by spectroscopic and chemical means.
Document emailed within 1 workday
Related Documents
Goldfarb, S.; Pitot, H.C. 1971: The regulation of beta-hydroxy-beta-methylglutaryl coenzyme a reductase in Morris hepatomas 5123C, 7800, and 9618A Cancer Research 31(12): 1879-1882Kirubagaran, R.; Joy, K.P. 1988: Inhibition of testicular 3 beta-hydroxy-delta 5-steroid dehydrogenase (3 beta-HSD) activity in catfish Clarias batrachus (L.) by mercurials Indian Journal of Experimental Biology 26(11): 907-908
O'Connor, D.M.; Crowe, M.J. 2003: Effects of beta-hydroxy-beta-methylbutyrate and creatine monohydrate supplementation on the aerobic and anaerobic capacity of highly trained athletes Journal of Sports Medicine and Physical Fitness 43(1): 64-68
Parrott, R.F. 1974: Effects of 17 beta-hydroxy-4-androsten-19-ol-3-one (19-hydroxytestosterone) and 5 alpha-androstan-17-beta-ol-3-one (dihydrotestosterone) on aspects of sexual behaviour in castrated male rats Journal of Endocrinology 61(1): 105-115
Kasai, H.; Mizutani, S.; Matsumoto, K. 1973: Detection of (3H)5 alpha-androstane-3 alpha,17 beta-diol and 3H17 beta hydroxy-5 alpha-androstan-3-one in mouse testes following administration of (3H) testosterone Acta Endocrinologica 74(1): 177-185
Lutsky, B.N.; Millonig, R.C.; Wojnar, R.J.; Free, C.A.; Devlin, R.G.; Varma, R.K.; Karanewsky, D.S. 1986: Androstene-17-thioketals. 2nd communication: pharmacological profiles of tipredane and (11 beta, 17 alpha)-17-(ethylthio)-9 alpha-fluoro-17-[2-(fluoroethyl)thio]-11 beta-hydroxy-androsta-1,4-dien-3-one, structurally novel 20-thiasteroids possessing potent and selective topical antiinflammatory activity Arzneimittel-Forschung 36(12): 1787-1795
Moore, G.E.; O'Donnell, S.R. 1970: A potent beta-adrenoreceptor blocking drug: 4-(2-hydroxy-3-isopropylaminopropoxy)indole Journal of Pharmacy and Pharmacology 22(3): 180-188
Back, P. 1978: Disorders of 3-beta-hydroxy-5-cholenic acid metabolism in intrahepatic cholestasis Verhandlungen der Deutschen Gesellschaft für Innere Medizin 84: 1106-1108
Saczewski, F.; Foks, H.; Sawlewicz, J.; Szulc, K. 1986: Studies of benzimidazole derivatives. XIII. Synthesis of various 2-alpha-hydroxy- and 2-beta-hydroxyalkyl-benzimidazoles Acta Poloniae Pharmaceutica 43(4): 299-307
Yushkova, L.A.; Fedulova, N.G.; Romanov, V.I.; Kretovich, W.L. 1975: Effect of cultivation conditions on the accumulation of poly-beta-hydroxy-butyric acid in Rhizobium lupini Prikladnaia Biokhimiia i Mikrobiologiia 11(2): 203-206
Hammerl, H.; Kränzl, C.; Nebosis, G.; Pichler, O.; Studlar, M. 1972: Metabolic studies and therapeutic experiences with the beta-receptor blockader 4-(2-hydroxy-3-isopropylamino-propoxy)-indol (LB 46) Arzneimittel-Forschung 22(6): 1055-1061
Laubie, M.; Cheymol, G.; Mouillé, P.; Gilbert, J.C.; Schmitt, H. 1973: Anti-arrhythmic effects of a beta-adrenolytic agent dl (hydroxy 2't-butylamino-3' propyloxy) 8-thiochromane (S 2395) Archives Internationales de Pharmacodynamie et de Therapie 201(2): 323-333
Azadian Boulanger, G.; Bonne, C.; Secchi, J.; Raynaud J P. 1974: The anti androgenic activity of r 2956 17 beta hydroxy 2 2 17 tri methyl estra 4 9 11 trien 3 one part 1 endocrinological profile Journal de Pharmacologie 5(4): 509-520
Smith, D.J.; Appleton, M.L.; Carlson, J.R.; Yost, G.S. 1996: Identification of beta-glucuronidase-resistant diastereomeric glucuronides of 3-hydroxy-3-methyloxindole formed during 3-methylindole metabolism in goats Drug Metabolism and Disposition: the Biological Fate of Chemicals 24(1): 119-125
Takenaka, F.; Ishihara, T.; Maruyama, Y.; Matsumoto, S.; Inoue, H. 1974: Effects of an adrenergic beta-receptor blockader, 2-acetyl-7-(2-hydroxy-3-isopropylamino) propoxybenzofuran hydrochloride on the cardiovascular system Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica 70(3): 385-397
Mellin, C.; Liu, Y.; Hacksell, U.; Björk, L.; Andén, N.E. 1987: A C2-methylated derivative of the 5-hydroxy-tryptamine-receptor agonist 8-hydroxy-2-(dipropylamino)tetralin (8-OH DPAT) Acta Pharmaceutica Suecica 24(4): 153-160
Xi, G.L.; Guo, X.Y.; Chen, R.L. 1980: Studies on antiasthmatic agents. II. Synthesis of some omega-(3-hydroxy-1,4-naphthoquinonyl-2)-alkanoic acids and mannich bases of 2-hydroxy-1,4-naphthoquinone Yao Xue Xue Bao 15(9): 548-554
Maccarrone, C.; Malta, E.; Raper, C. 1985: Comparison of the Arrhythmogenic Actions of (-)-Isoprenaline, Dobutamine and the selective beta 1-adrenoceptor agonist, (+/-)-(1-[3',4'-dihydroxyphenoxy] -2-hydroxy-[3",4"-dimethoxy phenethylamino]-propane)-oxalate (Ro 363) Arzneimittel-Forschung 35(3): 592-598
Hullot, P.; Poudrel, J.M.; Muller, A.; Escale, R.; Rossi, J.C.; Girard, J.P.; Bonne, C. 1997: Synthesis and biochemical/pharmacological profile of the novel leukotriene B4 receptor antagonist sodium (1S*, 3S*)-1-hydroxy-3-[(3 R*S*,E)-3-hydroxy-7-phenyl-1-hepten-1-yl]-1-cyclohexane acetate Arzneimittel-Forschung 47(1): 51-58
Takasu, A.; Ohya, K.; Sano, M. 1983: Determination of 20 alpha-hydroxy-9 beta,10 alpha-pregna-4,6-dien-3-one in plasma by selected ion monitoring Journal of Chromatography 272(2): 243-250