A C2-methylated derivative of the 5-hydroxy-tryptamine-receptor agonist 8-hydroxy-2- (dipropylamino) tetralin (8-OH DPAT)
Mellin, C.; Liu, Y.; Hacksell, U.; Björk, L.; Andén, N.E.
Acta Pharmaceutica Suecica 24(4): 153-160
1987
ISSN/ISBN: 0001-6675 PMID: 2964167 Document Number: 301557
Document emailed within 1 workday
Related Documents
Hullot, P.; Poudrel, J.M.; Muller, A.; Escale, R.; Rossi, J.C.; Girard, J.P.; Bonne, C. 1997: Synthesis and biochemical/pharmacological profile of the novel leukotriene B4 receptor antagonist sodium (1S*, 3S*)-1-hydroxy-3-[(3 R*S*,E)-3-hydroxy-7-phenyl-1-hepten-1-yl]-1-cyclohexane acetate Arzneimittel-Forschung 47(1): 51-58Komissarov, I.V.; Dolzhenko, A.T.; Obraztsova, O.G.; Zin'kovskaia, L.I. 1990: An analysis of the hypothermic action of 8-hydroxy-2-(di-N-propylamino)tetralin, 1-(2-pyrimidinyl)piperazine and its derivatives Biulleten' Eksperimental'noi Biologii i Meditsiny 109(3): 275-277
Chamberlain, J.; Offord, S.J.; Wolfe, B.B.; Tyau, L.S.; Wang, H.L.; Frazer, A. 1993: Potency of 5-hydroxytryptamine1a agonists to inhibit adenylyl cyclase activity is a function of affinity for the "low-affinity" state of [3H]8-hydroxy-N,N-dipropylaminotetralin ([3H]8-OH-DPAT) binding Journal of Pharmacology and Experimental Therapeutics 266(2): 618-625
Xi, G.L.; Guo, X.Y.; Chen, R.L. 1980: Studies on antiasthmatic agents. II. Synthesis of some omega-(3-hydroxy-1,4-naphthoquinonyl-2)-alkanoic acids and mannich bases of 2-hydroxy-1,4-naphthoquinone Yao Xue Xue Bao 15(9): 548-554
Koble, D.L.; Koons, J.C.; Fischer, L.J. 1985: Metabolism and disposition of the dopaminergic agonist 5-hydroxy-6-methyl-2-di-n-propylaminotetralin in the rat Drug Metabolism and Disposition: the Biological Fate of Chemicals 13(3): 305-311
Dupuis, L.; Brachet, P.; Puigserver, A. 1990: Oxidation of the supplemental methionine source L-2-hydroxy-4-methylthiobutanoic acid by pure L-2-hydroxy acid oxidase from chicken liver Journal of Nutrition 120(10): 1171-1178
Satokata, I.; Asami, T.; Otsuka, T.; Sakai, K. 1986: Rapid determination of 4-hydroxy-3-methoxymandelic (vanilmandelic) acid and 4-hydroxy-3-methoxyphenylacetic (homovanillic) acid in urine by liquid chromatography with electrochemical detection Rinsho Byori. Japanese Journal of Clinical Pathology 34(7): 817-822
Dooley, K.L.; Beland, F.A.; Bucci, T.J.; Kadlubar, F.F. 1984: Local carcinogenicity, rates of absorption, extent and persistence of macromolecular binding, and acute histopathological effects of N-hydroxy-1-naphthylamine and N-hydroxy-2-naphthylamine Cancer Research 44(3): 1172-1177
Levtchenko, N.K.; Osokin, D.M.; Torgov, I.V.; Arzamastzev, A.P.; Sokolova, T.M.; Tuguntaev, G.I. 1988: High-performance liquid chromatographic analysis of the by-products of the synthesis of ethynylestradiol, mestranol, 17 alpha-hydroxy-progesterone caproate and 17 alpha-hydroxy-6-dehydroprogesterone acetate Journal of Chromatography 456(2): 427-430
Pahwa, G.S.; Anand, K.K.; Johri, S.; Gupta, S.; Atal, C.K. 1987: Pharmacological and toxicological investigations of 7-hydroxy-4-phenyl-3(4-hydroxy-phenyl)-coumarin (OV1) Indian Journal of Experimental Biology 25(7): 450-453
Zieve, F.J.; Gutmann, H.R. 1971: Reactivities of the carcinogens, N-hydroxy-2-fluorenylacetamide and N-hydroxy-3-fluorenylacetamide, with tissue nucleophiles Cancer Research 31(4): 471-476
Luks, H.J.; Spratt, T.E.; Vavrek, M.T.; Roland, S.F.; Weisburger, J.H. 1989: Identification of sulfate and glucuronic acid conjugates of the 5-hydroxy derivative as major metabolites of 2-amino-3-methylimidazo[4,5-f]quinoline in rats Cancer Research 49(16): 4407-4411
Maccarrone, C.; Malta, E.; Raper, C. 1985: Comparison of the Arrhythmogenic Actions of (-)-Isoprenaline, Dobutamine and the selective beta 1-adrenoceptor agonist, (+/-)-(1-[3',4'-dihydroxyphenoxy] -2-hydroxy-[3",4"-dimethoxy phenethylamino]-propane)-oxalate (Ro 363) Arzneimittel-Forschung 35(3): 592-598
Desai, M.A.; Burnett, J.P.; Ornstein, P.L.; Schoepp, D.D. 1995: Cyclothiazide acts at a site on the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor complex that does not recognize competitive or noncompetitive AMPA receptor antagonists Journal of Pharmacology and Experimental Therapeutics 272(1): 38-43
Verimer, T.; Long, J.P.; Bhatnagar, R.K.; Koble, D.L.; Cannon, J.G.; Flynn, J.R.; Goodale, D.B.; Arnerić, S.P. 1981: Dopamine receptor stimulating activity of 5-hydroxy-6-methyl-2-aminotetralin derivatives Archives Internationales de Pharmacodynamie et de Therapie 250(2): 221-241
Hammerl, H.; Kränzl, C.; Nebosis, G.; Pichler, O.; Studlar, M. 1972: Metabolic studies and therapeutic experiences with the beta-receptor blockader 4-(2-hydroxy-3-isopropylamino-propoxy)-indol (LB 46) Arzneimittel-Forschung 22(6): 1055-1061
Takenaka, F.; Ishihara, T.; Maruyama, Y.; Matsumoto, S.; Inoue, H. 1974: Effects of an adrenergic beta-receptor blockader, 2-acetyl-7-(2-hydroxy-3-isopropylamino) propoxybenzofuran hydrochloride on the cardiovascular system Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica 70(3): 385-397
Mills, T.M.; Osteen, K.G. 1977: 17beta-Estradiol receptor and progesterone and 20alpha-hydroxy-4-pregnen-3-one content of the developing corpus luteum of the rabbit Endocrinology 101(6): 1744-1750
Satoh, M.; Sakai, T.; Sano, I.; Fujikura, K.; Koyama, H.; Ohshima, K.; Itoh, Z.; Omura, S. 1994: EM574, an erythromycin derivative, is a potent motilin receptor agonist in human gastric antrum Journal of Pharmacology and Experimental Therapeutics 271(1): 574-579
Ensinger, H.A. 1985: Differentiating aspects of opioid receptor binding by [3H](-) (1R,5R,9R,2''S)-5,9-dimethyl-2-tetrahydrofurfuryl-2'-hydroxy-6,7- benzomorphan hydrochloride ([3H]Mr 2034), a drug preferentially acting on kappa-receptors Arzneimittel-Forschung 35(1a): 447-451