Splenic involvement in infectious endocarditis. 5 clinical cases and 78 necropsies
Le Thi Huong, D.u.; Wechsler, B.; Cabane, J.; Herson, S.; Godeau, P.; Chomette, G.
Annales de Medecine Interne 135(3): 181-188
1984
ISSN/ISBN: 0003-410X PMID: 6742669 Document Number: 227412
Splenic involvement is a classical complication of infective endocarditis (IE). Clinical manifestations are rare, 5 out of 100 IE: unexpected rupture (1 case), abscess causing reinfection (2 cases), pseudo-tumour (1 case) and terminal infarction (1 case). In addition to a review of the literature, a post mortem histological study of the spleen of 78 cases of IE was undertaken. Splenic involvement did not seem to be the direct cause of death. Three types of lesions which may or may not be associated were observed: congestive inflammatory lesions, infarction (48 p. 100), abscess (6 p. 100). Splenic infarction usually results in scarring but may progress to abscess formation. Rupture was not observed in this autopsy series. Although splenic involvement is common at post mortem it gives rise to few symptoms. Persistant pyrexia and the appearance of local signs should lead to investigation of splenic complications and eventually, to surgical ablation.