A case of primary malignant lymphoma in the thyroid gland arising from pre-existing Hashimoto's disease
Kaneda, H.; Hara, M.; Yamatani, K.; Takahashi, K.; Kamimura, T.; Sasaki, H.
Gan no Rinsho. Japan Journal of Cancer Clinics 30(4): 373-377
1984
ISSN/ISBN: 0021-4949 PMID: 6547188 Document Number: 227297
Primary malignant lymphoma in the thyroid gland is relatively rare. It has been reported that primary malignant lymphomas comprise 0.8-8% of all thyroid malignancies. The relation to Hashimoto's disease is controversial. A 63-year-old woman with a 9-year history of diffuse goiter visited our hospital. A clinical diagnosis of Hashimoto's disease had previously been made. After 15 months, she noted the rapid growth of the goiter and enlargement of cervical lymph nodes . A cervical lymph node was biopsied, histologic examination lymphoma (large lymphoid-diffuse type). This suggests that malignant lymphoma in the thyroid gland may arise from pre-existing Hashimoto's disease.