A case of familial breast cancer
Nomizu, T.; Sekikawa, K.; Watanabe, I.; Endo, S.
Gan no Rinsho. Japan Journal of Cancer Clinics 30(10): 1251-1255
1984
ISSN/ISBN: 0021-4949 PMID: 6090724 Document Number: 226143
The occurrence of breast cancer in 5 members of a family is reported. No specificity of the location, staging or histological typing of the lesions was observed in these cancers. But the characteristics of "hereditary breast cancer", early onset and the occurrence of metachronous double cancers, were observed. As for heredity, it is suspected to be autosomal dominant trait; on the other hand it is more appropriate to assume a poly genic pattern. Recognizing the importance of familial cancer occurrence, it may be possible to detect early cancerous lesions in family members.