Possibilities of using ferromagnetic materials for targeted drug transport
Papisov, M.I.; Samokhin, G.P.; Smirnov, M.D.; Torcholin, V.P.; Smirnov, V.N.
Biulleten' Eksperimental'noi Biologii i Meditsiny 98(9): 372-374
1984
ISSN/ISBN: 0365-9615 PMID: 6207870 Document Number: 225624
Possibilities of using particles containing ferromagnetic materials and magnetic concentrated colloids for targeted drug transport were studied. Magnetic particles produced from Sephadex G-25 by ferromagnetic material fixation, polymer-modified iron particles 100 nm in diameter, and concentrated colloid solutions of Fe3O4 are retained in the marginal ear vein of the rabbit by magnetic field at .DELTA.H = 0.5 kHs/cm. The data on magnetic retention of the above-indicated agents in the vein, obtained by measuring 75Se and 131I activity, of labeled particles are presented.