Serotonin receptors in the frontal cortex of the rat. Influence of supralethal irradiation

Chanez, P.O.; Timmermans, R.; Gerber, G.B.

Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 178(5): 549-556

1984


ISSN/ISBN: 0037-9026
PMID: 6241028
Document Number: 224644
The density of the frontal cortex serotonin-2 receptors was determined after a supralethal irradiation (20 Gy) in Wistar rat. Using spiperone as ligand, we observed an important decrease in the density of serotonin-2 receptor and an increase in the dissociation constant receptor-ligand, 3 days after exposure.

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