Detection of HBs-Ag in the pancreas in cases of pancreatic carcinoma
Hohenberger, P.
Hepato-Gastroenterology 31(5): 239-241
1984
ISSN/ISBN: 0172-6390 PMID: 6510882 Document Number: 223499
Detection of HBs-Ag in the pancreatic juice in acute and chronic hepatic failure caused by hepatitis-B-infection leads to the assumption that parts of that virus are produced by the pancreas. We investigated pancreatic tissue obtained during Whipple's procedure in 51 cases of pancreatic carcinoma. In 5 specimens HBs-Ag was detected, mostly located in acinar cells and inside small ducts. In view of our knowledge of the carcinogenesis of human hepatocellular carcinoma, hepatitis B virus could produce an oncogenic effect in pancreatic carcinoma, too.
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