CCR5, RANTES and SDF-1 polymorphisms and mother-to-child HIV-1 transmission
Katz, D.A.; John-Stewart, G.C.; Richardson, B.A.; Majiwa, M.; Mabuka, J.M.; Lohman-Payne, B.; Farquhar, C.
International Journal of Immunogenetics 37(4): 301-305
2010
ISSN/ISBN: 1744-313X PMID: 20518834 DOI: 10.1111/j.1744-313x.2010.00924.xDocument Number: 223465
Summary Among 288 HIV-1-infected, breastfeeding women who received zidovudine prophylaxis and were followed with their infants in Nairobi, we found no associations between maternal genetic polymorphisms in CCR5 (59029G/A, 59353T/C, 59356T/C, 59402G/A), RANTES (-403G/A) and SDF-1 (3'801G/A) and mother-to-child HIV-1 transmission; plasma, cervical and breastmilk viral loads; or breastmilk chemokine concentrations.
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