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Basic research for light sensitive prosthesis. Electrically evoked potential in optic nerve of the albino rat

Hatayama, R.; Nakajima, A.; Yanashima, K.; Okisaka, S.

Nippon Ganka Gakkai Zasshi 88(10): 1273-1277

1984

ISSN/ISBN: 0029-0203
PMID: 6524534
Document Number: 223291
In order to determine the possible clinical of the optic nerve was studied in albino rats. Direct current or voltage stimulation of the optic nerve was performed after i.p. anesthesia; optical cortex evoked responses were recorded by polaroids. After unilateral or bilateral enucleation, the remaining optic nerves received the same stimulation and EER was compared. The light-sensitive prosthesis was used as a stimulator and the above procedure was repeated. After electrical simulation 4 or 5 peaks were gained within 20 ms in optical evoked responses. A similar pattern of EER was gained 5 h after enucleation. There was no change of EER pattern when using the light-sensitive prosthesis as stimulator.

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