REM-latency in neuroleptic drug withdrawal. A case report
Van Sweden, B.
Acta Psychiatrica Belgica 84(3): 235-239
1984
ISSN/ISBN: 0300-8967 PMID: 6148841 Document Number: 221963
This case report is one of the few observations in man showing REM-latency reduction as one of the neurophysiological consequences of abrupt neuroleptic suspension. One should take care not to attribute diagnostic significance to EEG or sleep-features which may be drug-dependent. The underlying neurochemical mechanisms are discussed, transient cholinergic overactivity is emphasized in neuroleptic withdrawal.