Agar cultures of blood forming cells from patients with various forms of hemopoietic dysplasia
Afanasjew, B.; Kulibaba, T.; Lukaschewa, T.; Smirnowa, G.; Sabelnia, T.; Podolzewa, E.
Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 38(3): 67-71
1983
ISSN/ISBN: 0044-2542 PMID: 6573822 Document Number: 220029
By means of a two-layer agar system the growth-types of blood-forming cells of altogether 47 patients with various forms of the haematopoietic dysplasia were investigated. It could be shown that a hypoplastic and a leukemic growth type as a rule represent a prognostically unfavourable criterion. The probability of a transformation to an acute leukosis is greater in such patients whose blood-forming cells show a leukemic growth in the agar culture. The results of clonization may be used for the differential diagnosis between haematopoietic dysplasia and a number of other diseases. The leukemic growth type was proved in 59% of the patients with haematopoietic dysplasia.