Passive protection of newborn calves against rotavirus by vaccination of their dams
Dauvergne, M.; Brun, A.; Soulebot, J.P.
Developments in Biological Standardization 53: 245-255
1983
ISSN/ISBN: 0301-5149 PMID: 6307780 Document Number: 219817
In field trials over two consecutive years (1980-81) inactivated rotavirus was injected in vaccine in oily excipient in 996 pregnant cows. There was a significant increase in the rate of colostral antibodies and a prolongation of the excretion of these antibodies into the milk up to and over 28 days after calving. Outbreaks of diarrhoea in calves born to vaccinated cows were less common and less serious and rotavirus was found to be playing a less significant role. A number of newborn calves (from vaccinated dams) with diarrhoea yielded bacteria (K99 essentially) and viruses such as coronavirus and bovine diarrhoea disease.