Long-term study of 150 mg. Bi-Profenid in patients followed at the Department of Rheumatology of Cochin Hospital
Amor, B.; Dougados, M.; Harrewyn, J.M.
La semaine des hopitaux organe fonde par l'Association d'enseignement medical des hopitaux de Paris 59(46): 3254-3257
1983
ISSN/ISBN: 0037-1777 PMID: 6318354 Document Number: 219510
The effectiveness and tolerance of Bi-Profenid 150 mg (two tablets a day) was evaluated in 37 patients under long-term treatment by retrospective analysis of case records. Mean duration of therapy was 15.5 months. Over this period improvement in the usual surveillance criteria was recorded. In 6 patients the "therapeutic follow-up test" allowed to decrease dosage to one tablet a day. Conversely, attempts at discontinuing the drug were followed by recurrence of pain. Tolerance was evaluated as excellent in 89% of cases and the only recorded side-effects were gastrointestinal.