Efficacy of a benzenedisulfonamide against experimental Fasciola hepatica infections in calves
Wyckoff, J.H.; Bradley, R.E.
American Journal of Veterinary Research 44(11): 2203-2204
1983
ISSN/ISBN: 0002-9645 PMID: 6650967 Document Number: 219505
Twenty-four calves were infected with 500 F. hepatica metacercariae and 14 weeks later 20 of them were treated, in 4 groups of 5, with benzenedisulfonamide subcutaneously at 2, 4, 8 or 16 mg/kg. The other 4 were left as untreated controls. The numbers of eggs in the faeces of the treated calves declined to zero by 2 weeks after treatment whereas the numbers passed by the controls increased. At necropsy the treated groups had 97.5, 99.5, 100 and 100% fewer flukes, respectively, than did the controls.