Amphotericin B induced alteration in membrane permeability: pH effects
Yorio, T.; Benoit, P.
Proceedings of the Western Pharmacology Society 26: 259-262
1983
ISSN/ISBN: 0083-8969 PMID: 6604280 Document Number: 219042
The effects of amphotericin B at varying pH on electrical properties and ionic fluxes of frog (Rana pipiens) skin were examined. Alkanization did not alter the effects on ion transport suggesting that the protective effects this procedure has in vivo may be physiological rather than a pharmacological antagonism of amphotericin B-induced renal damage.
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