Investigations of the turnover of adrenocortical mitochondria. XVI. Effects of ethidium bromide on the ACTH-induced elongation of the half-life of rat zona fasciculata mitochondria
Nussdorfer, G.G.; Mazzocchi, G.; Gottardo, G.
Anatomischer Anzeiger 153(5): 411-413
1983
ISSN/ISBN: 0003-2786 PMID: 6309034 Document Number: 218972
ACTH significantly increases the half-life of rat zona fasciculata mitochondria. Since ethidium bromide inhibits this effect of ACTH, the hypothesis is advanced that the ACTH-induced slowing-down of the degradation rate of adrenocortical mitochondria involves mitochondrial DNA reduplication and transcription.
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