Relationship of immunological status to infections complicating surgery of the large intestine
Nagy, A.; Baradnay, G.; Petri, I.; Zöllei, I.; Vattay, P.; Mozga, E.; Kováts, T.; Petri, G.
Zentralblatt für Chirurgie 108(20): 1272-1279
1983
ISSN/ISBN: 0044-409X PMID: 6649972 Document Number: 218930
The patients immuno-activity has a well-known importance for the outcome of postoperative complications. The authors evaluated the immuno-activity of 95 patients before selective, radical colorectal surgery: 1) 40% of the patients were anergic compared to healthy controls. 2) The incidence of wound infections was significantly higher in the anergic groups than in normal or hyperergic ones. 3) 25% and 50% decrease in wound sepsis has been observed in anergic and normal or hyperergic groups respectively after vaccination 7 to 10 days before operation with vaccine made of E. coli, Proteus, Klebsiella and Pseudomonas strains. The difference indicates the lowered immuno-reactivity on anergic patients.