Antacids in combination with other anti-ulcer agents
Fritsch, W.P.
Zeitschrift für Gastroenterologie 21 Suppl: 81-87
1983
ISSN/ISBN: 0044-2771 PMID: 6134405 Document Number: 218683
Antacids should not be combined with other anti-ulcer drugs such as carbenoxolone, metoclopramide, domperidone, sulpiride, di-citrato-bis-muthate and alginic acid. The effect of each single drug can be negatively influenced by combined application. H2-receptor-antagonists and sucralfate seem to be useful in combination with antacids. There is no evidence up to now that goals of therapy can be attained more effectively and in a shorter time than with either a drug alone. Before pirenzepine will be given in combination with antacids, bioavailability of the drug should be proved during antacid treatment. Today antacids in combination with other antiulcer drugs cannot be recommended for routine ulcer therapy.