Temporal decay of the effect of a single vagal stimulation on cardiac rhythm in the rabbit
Federici, A.; Sorrentino, G.; Nocera, L.; Ruccia, D.; Di Benedetta, C.
Bollettino della Societa Italiana di Biologia Sperimentale 59(12): 1935-1941
1983
ISSN/ISBN: 0037-8771 PMID: 6671051 Document Number: 218146
The negative chronotropic effect of a single stimulus randomly delivered through right, left or both vagi respectively, within the cardiac cycle was studied in anaesthetized rabbits. The effect was analyzed on the P-P cycles subsequent the stimulus application, calculating percentagewise the delay observed in definite time-lapses, equalized to two pre-stimulus cycles. The results indicate that the efficacy of the negative chronotropic effect of vagal stimulation shows the least delay the closer the stimulus to the wave, while the delay is higher when the stimulus is delivered within the central portion of the cycle.