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Effect of a vasopressin analog on the chemoreactive properties of sensorimotor cortex neurons

Kruglikov, R.I.; Brodskiĭ, B.L.; Koshtoiants, O.K.; Markarova, M.I.; Chippens, G.I.

Biulleten' Eksperimental'noi Biologii i Meditsiny 96(10): 3-5

1983

ISSN/ISBN: 0365-9615
PMID: 6626726
Document Number: 216664
Subcutaneous injection of 10 micrograms desglycilargininvasopressin (DG-AVP) does not alter the mean frequency of background unit activity of sensorimotor cortical neurons. However, the pattern of impulse activity is essentially changed. At the same time the reactions of sensorimotor cortical neurons to microiontophoretic administration of acetylcholine and noradrenaline experience definite changes. It is suggested that the DG-AVP-induced changes in chemoreactive properties of neurons underlie the effect of this peptide on the learning and memory.

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