Top Abstract Purchase Related
Home
>
Node
>
Subnode

Intake of 4-methylumbelliferyl-alpha-glucoside-entrapping liposome into guinea pig macrophages in vivo

Fujimori, K.; Yamamoto, A.; Yamada, M.; Yoshimura, T.; Shono, M.

Cellular and Molecular Biology 29(1): 19-22

1983

ISSN/ISBN: 0145-5680
PMID: 6347386
Document Number: 215076
The entry of 4-methylumbelliferyl-.alpha.-glucoside-entrapping liposome into guinea pig macrophages and degradation by .alpha.-glucosidase was evaluated using fluorescence microcytophotometry. The amount of fluorescence formed by cleavage of glucosidic bond was parallel with incubation times in the peritoneal cavity. Liposomes phagocytized by macrophages apparently fuse with lysosomes and the contained 4-methylumbelliferyl-.alpha.-glucosides are broken down by .alpha.-glucosidase in lysosomes. This procedure was provided for cytochemical staining of .alpha.-glucosidase in a single macrophage.

Document emailed within 1 workday
Secure & encrypted payments

Li, Y.; Liu, X.; Xue, S.Z. 1998: Antidotal effect of glucoside extracted from Astragalus membranaceus on dimethoate intoxication in guinea pigs La Medicina del Lavoro 89(Suppl 2): S136-S141
Foong, W.C.; Green, K.L. 1988: Association of liposome-entrapped [3H]methotrexate with thioglycollate-elicited macrophages in-vitro Journal of Pharmacy and Pharmacology 40(3): 171-175
Schroit, A.J.; Fidler, I.J. 1982: Effects of liposome structure and lipid composition on the activation of the tumoricidal properties of macrophages by liposomes containing muramyl dipeptide Cancer Research 42(1): 161-167
Das, N.; Raay, B.; Basu, M.K. 1999: Effect of angiotensin Ii on liposome uptake by the rat brain in vivo Indian Journal of Experimental Biology 37(9): 871-875
Nicolau, C.; Le Pape, A.; Soriano, P.; Fargette, F.; Muh, J.P.; Juhel, M.F. 1982: In vivo transfer and expression of the liposome encapsulated rat insulin gene Progress in Clinical and Biological Research 102 Pt A: 321-330
Ivorra, M.D.; Paya, M.; Villar, A. 1990: Effect of beta-sitosterol-3-beta-D-glucoside on insulin secretion in vivo in diabetic rats and in vitro in isolated rat islets of Langerhans Die Pharmazie 45(4): 271-273
Bakker-Woudenberg, I.A.; Lokerse, A.F.; Roerdink, F.H. 1989: Antibacterial activity of liposome-entrapped ampicillin in vitro and in vivo in relation to the lipid composition Journal of Pharmacology and Experimental Therapeutics 251(1): 321-327
Pelling, J.C.; Slaga, T.J.; DiGiovanni, J. 1984: Formation and persistence of DNA, RNA, and protein adducts in mouse skin exposed to pure optical enantiomers of 7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyre ne in vivo Cancer Research 44(3): 1081-1086
Ubysz-Jerzmanowska, K. 1972: Effect of diphtheria toxins on guinea pig macrophages. 3. Lysosomes of peritoneal macrophages subjected to action of diphtheria toxins Medycyna Doswiadczalna i Mikrobiologia 24(3): 201-206
Terletskaia, I.T.; Trikash, I.O. 1994: Effect of pH of the medium on the liposome fusion process after treatment with alpha-latrotoxin Biokhimiia 59(3): 441-448
Suntres, Z.E.; Hepworth, S.R.; Shek, P.N. 1993: Pulmonary uptake of liposome-associated alpha-tocopherol following intratracheal instillation in rats Journal of Pharmacy and Pharmacology 45(6): 514-520
Yin, J.; Zhai, S.; Guo, W.; Hu, Y.; Shi, L. 2002: Protective and rescue effects of transgenic bFGF/GFP expression mediated by cationic liposome on gentamicin-induced guinea pig cochlear toxicity Zhonghua Yi Xue Za Zhi 82(17): 1192-1194
Agostini, C.; Zambello, R.; Trentin, L.; Cerutti, A.; Enthammer, C.; Facco, M.; Milani, A.; Sancetta, R.; Garbisa, S.; Semenzato, G. 1995: Expression of TNF receptors by T cells and membrane TNF-alpha by alveolar macrophages suggests a role for TNF-alpha in the regulation of the local immune responses in the lung of HIV-1-infected patients Journal of Immunology 154(6): 2928-2938
Lu, D.; Benjamin, R.; Kim, M.; Conry, R.M.; Curiel, D.T. 1994: Optimization of methods to achieve mRNA-mediated transfection of tumor cells in vitro and in vivo employing cationic liposome vectors Cancer Gene Therapy 1(4): 245-252
Debs, R.J.; Fuchs, H.J.; Philip, R.; Brunette, E.N.; Düzgüneş, N.; Shellito, J.E.; Liggitt, D.; Patton, J.R. 1990: Immunomodulatory and toxic effects of free and liposome-encapsulated tumor necrosis factor alpha in rats Cancer Research 50(2): 375-380
Ubysz-Jerzmanowska, K. 1972: Effect of diphtheria toxin on guinea pig macrophages Polski Tygodnik Lekarski 27(37): 1455-1456
Gaertner, H.J.; Flössel, C.; Müller, M. 1984: Procoagulatory activity of macrophages and monocytes of the guinea pig Biomedica Biochimica Acta 43(4): 429-438
Lindholm, T.S.; Nilsson, O.S.; Lindholm, T.C. 1985: 1-Alpha-OH-cholecalciferol (1-alpha-OH-D3) and optimal calcium intake in calcium deficiency osteoporosis mediated by parathyroid activity morphologic and biochemical changes in adult male rats Acta Vitaminologica et Enzymologica 7(1-2): 39-47
Nomura, T.; Nakajima, S.; Kawabata, K.; Yamashita, F.; Takakura, Y.; Hashida, M. 1997: Intratumoral pharmacokinetics and in vivo gene expression of naked plasmid DNA and its cationic liposome complexes after direct gene transfer Cancer Research 57(13): 2681-2686
Johnson, C.S.; Pourbohloul, S.C.; Furmanski, P. 1991: Negative regulators of in vivo erythropoiesis: interaction of IL-1 alpha and TNF-alpha and the lack of a strict requirement for T or NK cells for their activity Experimental Hematology 19(2): 101-105