Top Abstract Purchase Related
Home
>
Node
>
Subnode

NADPase and NADase in the peritoneal macrophages of mice

Nemchinskaia, V.L.; Pokrovskaia, T.G.; Mozhenok, T.P.; Braun, A.D.

Tsitologiia 25(7): 799-804

1983

ISSN/ISBN: 0041-3771
PMID: 6312646
Document Number: 213220
Murine peritoneal macrophages are able to hydrolyse NAD+ and NADP+. The NADPase activity exceeds that of NADase by 22-24%. The pH optima for both the enzymes are, respectively, 6.0 and 7.0. NAD hydrolysis is considerably activated by Mg2+, whereas NADP hydrolysis remains not affected. NAD+ does not change NADPase activity, while NADase activity is inhibited by NADP by 25-30%. A diazonium salt of sulfanilic acid, known to be an inhibitor of cell plasma membranes, does not affect NADP+ hydrolysis and causes a 20-30% retardation of NAD+ hydrolysis. The data obtained suggest that murine peritoneal macrophages contain two hydrolytic enzymes: NADase and NADPase.

Document emailed within 1 workday
Secure & encrypted payments

Miroshnichenko, S.M.; Kovalenko, G.A.; Tsirel'nikov, N.I.; Panin, L.E. 2013: Comparative analysis of morphofunctional indicators of peritoneal macrophages in mice of the cancer line A/SN and white outbred mice Voprosy Onkologii 59(6): 771-776
An, H-Jin.; Um, J-Young.; Na, H-Jeong.; Jeong, S.; Kim, H-Min.; Hong, S-Heon. 2007: Activation of inducible nitric oxide synthase by Kagamjuaguiem in peritoneal macrophages in mice Indian Journal of Medical Research 125(6): 740-746
Kelkar, S.D. 1987: In vivo opsonization of Japanese encephalitis virus by peritoneal macrophages in infant mice Acta Virologica 31(3): 269-270
Akhtarieva, A.A.; Dolgushin, I.I.; Gabidullin, Z.G.; Gabidullin, I.Z.; Kamalova, A.A. 2007: Influence of termolabile enterotoxin of Enterobacter cloacae on phagocytic activity of mice peritoneal macrophages Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 4: 58-61
Salem, A.E.; Rashwan, E.A.; Abo-el-Nazar, S.Y. 1992: Assessment of interleukin-1 activity of peritoneal macrophages in mice infected with Schistosoma mansoni before and after praziquantel administration Journal of the Egyptian Society of Parasitology 22(3): 703-708
Cheung, S.C.; Chattopadhyay, S.K.; Hartley, J.W.; Morse, H.C.; Pitha, P.M. 1991: Aberrant expression of cytokine genes in peritoneal macrophages from mice infected with LP-BM5 MuLV, a murine model of AIDS Journal of Immunology 146(1): 121-127
Berdel, W.E.; Munder, P.G. 1981: Metastatic growth of 3-Lewis lung carcinoma in mice treated with alkyl-lysophospholipids and lysophospholipid-induced peritoneal macrophages Anticancer Research 1(6): 397-402
Sodhi, S.; Ganguly, N.K.; Malla, N.; Mahajan, R.C. 1989: Lymphokine mediated microbicidal activity of peritoneal macrophages from Leishmania donovani infected and drug treated BALB/c mice Japanese Journal of Experimental Medicine 59(3): 103-108
Wellek, B.; Kessel, G.; Loos, M.; Hahn, H. 1977: Increase of phagocytic activity and new appearance of a C4b (guinea pig) recognizing capability in peritoneal macrophages from Corynebacterium parvum and thioglycollate-stimulated mice Monographs in Allergy 12: 105-110
Weinberg, J.B. 1981: In vivo modulation of macrophage tumoricidal activity: enhanced tumor cell killing by peritoneal macrophages from mice given injections of sodium periodate Journal of the National Cancer Institute 66(3): 529-533
De Bakker, J.M.; De Wit, A.W.; Onderwater, J.J.; Ginsel, L.A.; Daems, W.T. 1985: On the origin of peritoneal resident macrophages. I. DNA synthesis in mouse peritoneal resident macrophages Journal of Submicroscopic Cytology 17(2): 133-139
Macfarlan, R.I.; Burns, W.H.; White, D.O. 1977: Two cytotoxic cells in peritoneal cavity of virus-infected mice: antibody-dependent macrophages and nonspecific killer cells Journal of Immunology 119(5): 1569-1574
Chace, J.H.; Fleming, A.L.; Gordon, J.A.; Perandones, C.E.; Cowdery, J.S. 1995: Regulation of differentiation of peritoneal B-1a (CD5+) B cells. Activated peritoneal macrophages release prostaglandin E2, which inhibits IgM secretion by peritoneal B-1a cells Journal of Immunology 154(11): 5630-5636
De Bakker, J.M.; De Wit, A.W.; Koerten, H.K.; Ginsel, L.A.; Daems, W.T. 1985: On the origin of peritoneal resident macrophages. III. EM-immunocytochemical studies on the origin of mouse peritoneal resident macrophages Journal of Submicroscopic Cytology 17(2): 153-159
Sułowicz, W. 1990: Activity of some lysosomal enzymes in peritoneal macrophages of patients with end-stage renal failure treated by intermittent peritoneal dialysis Folia Haematologica 117(5): 663-667
Romanova, L.A.; Lugovskaia, S.A.; Shutov, E.V.; Levina, A.A.; Frolova, O.E.; Korovina, V.I. 2001: Functional activity of monocytes-macrophages and neutrophils of blood and peritoneal effluent in patients with end-stage kidney failure maintained by permanent peritoneal dialysis at an outpatient setting Klinicheskaia Laboratornaia Diagnostika 3: 44-47
Yamamoto, N.; Homma, S.; Millman, I. 1991: Identification of the serum factor required for in vitro activation of macrophages. Role of vitamin D3-binding protein (group specific component, Gc) in lysophospholipid activation of mouse peritoneal macrophages Journal of Immunology 147(1): 273-280
Krasil'nikov, M.A.; Khramtsova, S.N.; Basiuk, E.I. 1991: The role of peritoneal macrophages in realizing the growth inhibiting effect of glucocorticoids on reinoculated murine hepatoma 22 cells: the effect of hydrocortisone on the cytotoxic activity and metabolism of phospholipids by macrophages Biokhimiia 56(7): 1281-1287
Kauma, S.; Clark, M.R.; White, C.; Halme, J. 1988: Production of fibronectin by peritoneal macrophages and concentration of fibronectin in peritoneal fluid from patients with or without endometriosis Obstetrics and Gynecology 72(1): 13-18
Ubysz-Jerzmanowska, K. 1972: Effect of diphtheria toxins on guinea pig macrophages. 3. Lysosomes of peritoneal macrophages subjected to action of diphtheria toxins Medycyna Doswiadczalna i Mikrobiologia 24(3): 201-206